Some uncertainties are resolvable. The insurance industry’s actuarial tables and the gambler’s roulette wheel both yield to the tools of probability theory. Most situations in life, however, involve a deeper kind of uncertainty, a radical uncertainty for which historical data provide no useful guidance to future outcomes.

Jim Simons is the greatest moneymaker in modern financial history. No other investor can touch his record. Since 1988, Renaissance’s signature Medallion fund has generated average annual returns of 66%. The firm has earned profits of more than $100 billion—Simons is worth $23 billion.

Through a series of counterintuitive concepts and contemporary case studies based on her firsthand experience of investing in 50 markets around the globe, Rupal Bhansali describes in her new book, The Need for Non-Consensus Investing, how to perform differentiated fundamental research to uncover mispriced stocks. Bhansali candidly shares her failures and mistakes as well as her successes and triumphs.